Looking at the sales and prfit graphs for HD, they dropped a big one a few years back and have reacted now by dumping the fluff from the edges. I think they had desires to become something they are not. HD sell a lifestyle and toys to go with that (I guess all the major bike firms do), and they looked outside that with the 'radical' Buell's and the sporty MVs - both also targeted at a pretty small client base and one that overlaps with HD - so good choices I would guess. Dont think they took account of the view of HD from outside USA, where HD is as a niche market for paleolithic technology. I think in the US they are seen as pretty mainstream. Looking at the data they should have got out 2 or more years ago, and good on them for sticking with it, but probably bad business. Now they have an economy where niche high value prducts are being squeezed and a badly damaged business from the losse on Buell and MV. Will be intersting to see what they do.
Is Buell a loss - who knows - nice ideas and often the real innovation is not in a new idea bu te combination of a number of old ideas into a new package (Innovation and entrepreneurial rather than creative and new) and I think Buell did this, but was so much about what an interesting set of components could be wrapped around a HD lump. Maybe a Buell with a MV lump would have been more challenging to the market and break open niches that the HD lump would close.
Someone will buy the MV name and loose a pot of money trying to make it work, the Italan marques are as evocative as the British and the American, and people seem to want to throw money at them.
John Bloor did this well, he took a name with a history but did nto try to build that history anew until they had a reputation of their own. Dallied with 4 cylinders etc before hitting on a USP of the triple. Now can afford to make the 'Bonnie'. Had he done this first - as would be the temptation - I think they would have sunk. Mind he was not a motorcyclist but a business man who wanted to move some of his time from building into manufacturing.
What wold be interesting is if some one like Dyson were to take on an old marque with the intent of making innovative electric bikes. Mind the idea of a bike with a 2000rpm spin speed...

So is the demise of any manufacturer a loss - depends on your point of view. Yes - it is a pity as some of the variety has gone from a very conservative sector, and the no - the demise of any business is never a loss it is evolution, if the ideas were any good they will be picked up by others.
R